1.5.1 firmware for me, and some SCUMMVM games where among the top things I really wanted to get working, well, in my case I found out that some games would crash on launch with default settings, issues are (in my experience at least) all audio related, had to change the default audio and midi settings (select a game and click options from main SCUMMVM menu), unfortunately have already repackaged and wrapped the RG350 to give it as Christmas gift so can't access it to tell the exact audio config but there aren't many options.
I was able to get running perfectly (with audio/music):
- Monkey Island 1 and 2
- Indiana Jones and The Fate Of Atlantis
- Sam and Max
- Day Of The Tentacle
Haven't tried any other as those where the ones I really cared for
Specifically, I got crashes on launch with Monkey Island 2 and Indiana Jones while Monkey Island 1 would work with default settings (Sam and max and Day of the tentacle where tested only after the audio "fix" thing, so don't know if they would have crashed for me).