2nd design is the best. But needs touchpad support as well, if we want this to replace our laptops.
It definitely needs a keyboard, I wouldn't need a laptop anymore if it had keyboard and touchpad support. One thing that would be awesome is to mimick Ps3 bluetooth keyboard's mouse behaviour. The Keys are flattish (like blackberry curve 9900) but they are also a touchpad if you swipe your fingers across. This would be the killer laptop replacement.
Also, I wouldn't mind having the option to run android on it. Or just put the keyboard into the existing GPD XD, I don't care about windows.